Latest Updates & News
A New Era in Lung Cancer Treatment: FDA Approves Augtyro on November 15, 2023
What is Augtyro prescribed for? Augtyro is prescribed for the treatment of adult patients with locally advanced or metastatic ROS1-positive non-small cell lung cancer. What is Augtyro and what does it do? Augtyro, pronounced Aug-TYE-ro, (generic name: repotrectinib) is a newly FDA-approved medication for treating a specific type of lung cancer called...
Can Adding Pembrolizumab to Chemotherapy Improve Outcomes for Early Triple-Negative Breast Cancer?
What Did the Research Discover? This study examined whether adding pembrolizumab (Keytruda), an immune checkpoint inhibitor, to standard chemotherapy before surgery could improve outcomes for patients with early-stage triple-negative breast cancer (TNBC). In this large phase 3 trial, 1,174 patients with stage II or III TNBC were randomly assigned to receive either:...
Research Progress for Chronic Bronchitis: Sulforaphane Strengthens Lung Defenses
What did the research discover? Researchers studied how activating a specific protein called Nrf2 could help the immune cells in the lungs, called alveolar macrophages, fight bacterial infections in chronic obstructive pulmonary disease (COPD). COPD makes it harder for these immune cells to remove harmful bacteria, leading to frequent lung infections and worsening...
Do All Men with Prostate Cancer Get the Same Treatment? A Look at Racial and Ethnic Gaps
What Are Current Prostate Cancer Treatments? Treating advanced prostate cancer often involves lowering the levels of male hormones (called androgens) in the body. This is because prostate cancer cells usually need these hormones to grow. One common treatment is called androgen deprivation therapy (ADT), which uses special medicines to stop the body from making these...
New Light on Osteoarthritis: Innovative Imaging Techniques Unveil Early Joint Damage
What did the research discover? Researchers explored quantitative imaging techniques that assess the biochemical composition of articular cartilage, offering early detection of osteoarthritis (OA) and new pathways for disease-modifying treatments. Traditional imaging methods like X-rays and standard MRIs fail to detect early-stage OA, while newer imaging techniques...
New Combination Therapy Shows Promise for Advanced Urinary Tract Cancer
What Did the Research Discover? Researchers conducted a phase 3 clinical trial to evaluate whether adding nivolumab, an immune therapy, to the standard chemotherapy drugs gemcitabine and cisplatin would improve survival for patients with advanced urothelial carcinoma (a type of bladder cancer). The study included 608 patients with unresectable or metastatic...
New Discovery Could Lead to Better Treatments for Rheumatoid Arthritis
What did the research discover? Researchers created a detailed map of the cells in the synovial tissue of people with rheumatoid arthritis (RA) by studying over 314,000 cells from 79 donors. They found six different types of cell patterns, called cell-type abundance phenotypes (CTAPs), which show various immune cell compositions in the inflamed joint tissue. These...