Do GLP 1 Medications Worsen Depression?

Sep 9, 2026

This Study Looked at Nearly 100,000 People to Find Out GLP-1 receptor agonists are widely used to treat type 2 diabetes and obesity. But in recent years, concerns have been raised about whether these medications might worsen depression, anxiety, or even increase the risk of self-harm. A large national study published in The Lancet Psychiatry examined this question closely — and the findings may be reassuring for both patients and clinicians.

Reported by

Reviewed by

You May Also Like