What is Triple Negative Breast Cancer?

Jun 30, 2026

Triple-negative breast cancer, or TNBC, is one of the most aggressive forms of breast cancer. It’s called “triple negative” because the cancer cells lack three common receptors — estrogen, progesterone, and HER2 — that some other breast cancers have. That matters because most targeted therapies work by attaching to one of those receptors.

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