What Are Current Prostate Cancer Treatments? Treating advanced prostate cancer often involves lowering the levels of male hormones (called androgens) in the body. This is because prostate cancer cells usually need these hormones to grow. One common treatment is called androgen deprivation therapy (ADT), which uses special medicines to stop the body from making these...
What Did the Research Discover? Researchers conducted a phase 3 clinical trial to evaluate whether adding nivolumab, an immune therapy, to the standard chemotherapy drugs gemcitabine and cisplatin would improve survival for patients with advanced urothelial carcinoma (a type of bladder cancer). The study included 608 patients with unresectable or metastatic...
What Did the Research Discover? Researchers studied sacituzumab govitecan (SG) as a possible treatment for advanced endometrial cancer (EC) in patients who had already undergone chemotherapy and immunotherapy. The study was part of the TROPiCS-03 trial, which included patients with various metastatic solid tumors. In this phase II study, 41 patients with advanced EC...
What Did the Research Discover? This study evaluated the effectiveness of nivolumab combined with gemcitabine–cisplatin compared to gemcitabine–cisplatin alone in patients with previously untreated advanced urothelial carcinoma. The research found that patients receiving the nivolumab combination had significantly longer overall survival (21.7 months vs. 18.9...
What Did the Research Discover? This study examined whether adding pembrolizumab (Keytruda), an immune checkpoint inhibitor, to standard chemotherapy before surgery could improve outcomes for patients with early-stage triple-negative breast cancer (TNBC). In this large phase 3 trial, 1,174 patients with stage II or III TNBC were randomly assigned to receive either:...
What did the research discover? Researchers tested if a voice-activated therapy using cognitive behavioral therapy for insomnia (CBT-I) could help breast cancer survivors who have trouble sleeping. CBT-I is a type of talk therapy that teaches ways to improve sleep by changing habits and thoughts that make it hard to rest. This therapy was delivered through a smart...