What Did the Research Discover? Researchers studied retinitis pigmentosa (RP), an inherited eye disease that causes vision loss due to the death of light-sensitive cells in the retina. RP affects about 1 in 5,000 people worldwide, leading to symptoms like night blindness and tunnel vision. The condition is caused by genetic mutations, and more than 90 genes have...
What did the research discover? This study evaluated the effectiveness of the CAPTURE screening tool in identifying undiagnosed, clinically significant chronic obstructive pulmonary disease (COPD) in primary care settings. The CAPTURE tool consists of five questions about symptoms and exposure, along with a lung function test for some patients. Researchers analyzed...
What did the research discover? Researchers studied how activating a specific protein called Nrf2 could help the immune cells in the lungs, called alveolar macrophages, fight bacterial infections in chronic obstructive pulmonary disease (COPD). COPD makes it harder for these immune cells to remove harmful bacteria, leading to frequent lung infections and worsening...
What did the research discover? This study tested whether methotrexate, a drug used to treat rheumatoid arthritis, could help reduce knee pain and stiffness in people with knee osteoarthritis (KOA). Researchers conducted a randomized, double-blind, placebo-controlled trial across 15 clinics in the United Kingdom, including 207 participants with moderate to severe...
What did the research discover? This study explored how amyloid beta (Aβ), a protein linked to Alzheimer’s disease (AD), accelerates the process of protein insolubility that naturally occurs with aging. Protein insolubility happens when proteins clump together and lose their normal function, a hallmark of neurodegenerative diseases like Alzheimer’s, Parkinson’s, and...
What did the research discover? This study examined whether short-term side effects after receiving an mRNA COVID-19 vaccine are linked to a stronger immune response. Researchers followed 363 adults in the San Francisco Bay Area who received two doses of either the Pfizer (BNT162b2) or Moderna (mRNA-1273) vaccine and had no prior COVID-19 exposure. They measured...