What is Jaypirca prescribed for?
Jaypirca is prescribed to treat relapsed or refractory mantle cell lymphoma in adults who have had at least two lines of systemic therapy, including a BTK inhibitor.
What is the name of the drug and what does it do?
The name of the drug is Jaypirca, pronounced JAY-PIHR-KAA, (generic name: pirtobrutinib). It is a prescription medication approved for the treatment of mantle cell lymphoma, a type of blood cancer, in adults who have received at least two prior therapies.
How does it work?
Jaypirca works by inhibiting Bruton’s tyrosine kinase (BTK), an enzyme that plays a critical role in the growth and survival of B-cells, which are a type of white blood cell.
By blocking BTK, Jaypirca helps to stop the growth and spread of cancerous B-cells in mantle cell lymphoma.
What did the research discover?
Clinical trials demonstrated that Jaypirca is effective in treating mantle cell lymphoma in patients who have already received multiple therapies.
In the studies, a significant number of patients experienced a reduction in tumor size or complete remission.
These results indicate that Jaypirca can provide a valuable treatment option for patients with this challenging form of lymphoma.
What are some of the side effects?
The side effects listed are from the product manufacturer. As health scientists, we share this information to keep you informed without causing undue worry. Many side effects diminish over time, and not all patients experience them. If prescribed medication, take it as directed and consult your healthcare professional if you have any concerning side effects.
- Fatigue
- Diarrhea
- Decreased appetite
- Bruising
- Muscle or joint pain
- Upper respiratory tract infections
- Nausea
- Fever
What are the dosage recommendations and how is it prescribed?
Jaypirca is taken orally, with the recommended dose being 200 mg once daily. It can be taken with or without food.
Patients should follow their healthcare provider’s instructions precisely and not miss doses.
Regular monitoring by a healthcare provider is necessary to manage any side effects and to adjust the dosage if needed.
Source:
- FDA. Drug Trials Snapshots: Jaypirca. Available from: FDA’s Drug Trials Snapshot for Jaypirca. Accessed 16 July 2024.
- Drug Trials Snapshots: JAYPIRCA. FDA. Available from: https://www.fda.gov/drugs/drug-approvals-and-databases/drug-trials-snapshots-jaypirca. Accessed 16 July 2024.
