What Did the Research Discover? Researchers in Denmark studied whether thiazide diuretics, a common type of blood pressure medication, increase the risk of low sodium levels (hyponatremia). They analyzed medical records from 2014 to 2018, looking at over 180,000 people who started different blood pressure treatments. The study found that people who took thiazide...
What Did the Research Discover? This study evaluated the effectiveness of nivolumab combined with gemcitabine–cisplatin compared to gemcitabine–cisplatin alone in patients with previously untreated advanced urothelial carcinoma. The research found that patients receiving the nivolumab combination had significantly longer overall survival (21.7 months vs. 18.9...
What Did the Research Discover? This study examined whether adding pembrolizumab (Keytruda), an immune checkpoint inhibitor, to standard chemotherapy before surgery could improve outcomes for patients with early-stage triple-negative breast cancer (TNBC). In this large phase 3 trial, 1,174 patients with stage II or III TNBC were randomly assigned to receive either:...
What Did the Research Discover? Menopausal vasomotor symptoms (VMS)—such as hot flashes and night sweats—are common experiences for many women during menopause. While previous research has established a link between obesity and the presence of menopausal symptoms, this study sought to explore whether the severity of these symptoms is also influenced by body weight...
What Did the Research Discover? Researchers investigated whether low-dose aspirin could reduce the risk of developing type 2 diabetes in older adults. The study included 16,209 people aged 70 and older (or 65 and older for some U.S. minority groups) who were generally healthy and did not have diabetes at the start of the study. Participants were randomly assigned to...
What Did the Research Discover? Researchers studied whether benzodiazepine use is linked to a higher risk of dementia or cognitive decline in older adults. The study followed 3,434 participants aged 65 and older in Seattle, Washington, who did not have dementia at the beginning of the study. They were observed for an average of 7.3 years, with cognitive tests given...