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New Targeted Therapies Are Expanding Options for Hormone-Positive Breast Cancer

New Targeted Therapies Are Expanding Options for Hormone-Positive Breast Cancer

Hormone receptor-positive, HER2-negative breast cancer is the most common subtype of breast cancer. While treatments have improved significantly over the years, many patients eventually develop resistance to standard therapies, allowing cancer to continue growing despite treatment.

Researchers have increasingly focused on a pathway known as PI3K/AKT/mTOR/PTEN, which plays a critical role in cancer growth and survival. New therapies targeting this pathway are creating additional treatment options and helping move breast cancer care toward a more personalized future.

Reassessing The Efficacy of Vitamin D and Calcium Supplements for Bone Health

Reassessing The Efficacy of Vitamin D and Calcium Supplements for Bone Health

For years, vitamin D and calcium supplements have been promoted as a way to strengthen bones and prevent fractures. Millions of adults take them daily, believing they offer strong protection against osteoporosis and bone loss.
But a major review published in The BMJ is challenging that belief.
Researchers analyzed 69 randomized controlled trials involving more than 153,000 adults. They examined whether vitamin D, calcium, or a combination of both could reduce fractures and falls.
The results were surprising.

Here Are The New Cholesterol Guidelines

Here Are The New Cholesterol Guidelines

If your doctor has talked to you about cholesterol before, the conversation may sound a little different next time.
The newest cholesterol guidelines shift the focus from simply treating high cholesterol as a number to preventing heart disease much earlier.

Could a Gene Help Predict Which Endometrial Cancers Are Most Likely to Return?

Could a Gene Help Predict Which Endometrial Cancers Are Most Likely to Return?

Not all endometrial cancers behave the same way. Some tumors are treated successfully and never return, while others come back despite appearing low-risk when first diagnosed. This has led researchers to look beyond traditional pathology and focus on the genetic changes that may influence how a cancer behaves.

One gene receiving increasing attention is CTNNB1. Recent research suggests that mutations in this gene may help identify patients who face a higher risk of recurrence, even when their cancer appears less aggressive under a microscope. As precision medicine continues to advance, CTNNB1 could become an important tool for improving treatment decisions and patient outcomes.

First Over-the-Counter Continuous Glucose Monitor for Children Cleared by the FDA

First Over-the-Counter Continuous Glucose Monitor for Children Cleared by the FDA

The U.S. Food and Drug Administration recently cleared for marketing the first over-the-counter (OTC) continuous glucose monitor (CGM) for children, Dexcom Inc.’s Stelo Glucose Biosensor System, an integrated CGM (iCGM) indicated for people two years of age and older who do not use insulin. The FDA previously cleared the Stelo Glucose Biosensor System OTC for individuals 18 years and older in March 2024.

A Foodborne Parasite on the Rise?  What You Should Know About Cyclosporiasis

A Foodborne Parasite on the Rise? What You Should Know About Cyclosporiasis

Health officials are investigating a multistate increase in cyclosporiasis, an intestinal illness caused by the parasite Cyclospora cayetanensis. Recent cases have been reported in multiple states, and investigators are working to identify the food source responsible for the outbreak. Because the parasite is often linked to fresh produce, outbreaks can affect people across several regions before the source is identified.